According to the University of Oxford study, mixing doses of Covid-19 vaccines from Pfizer inc. and Astrazeneca plc creates a strong immune response.
This result from the university could enable greater flexibility in the use of scarce supplies.
A mixed schedule of the Pfizer shot followed by the Astra vaccine, and vice versa, resulted in high concentrations of antibodies against Covid-19 when given four weeks apart, researchers reported on Monday in the lancet medical journal.
The best T-cell response came from Astra followed by Pfizer, and the highest antibody response was seen from two doses of Pfizer.
“This argues for flexibility in use of these schedules, where local circumstances require it,” Matthew Snape, an Oxford professor who led the trial, said in a press briefing.
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